Precision, Performance, and Scale-Up Versatility in Pharmaceutical Laboratories
The Large-Scale Rotary Evaporator for Pharmaceutical Applications is an essential component in pharmaceutical manufacturing and research, enabling efficient distillation and solvent recovery under reduced pressure. As production demands evolve, especially in pilot-scale and GMP-compliant facilities, the need for high-capacity rotary evaporation systems becomes critical. The solution offered by Equilrxnlab through its AKR-1020 Rotary Evaporator addresses these challenges with robust technical specifications and advanced control features tailored for pharmaceutical applications.
Evaporation of solvents from sensitive or high-value compounds requires not only precise temperature control but also stable vacuum environments and substantial volume capacity. The Large-Scale Rotary Evaporator for Pharmaceutical Applications delivers on all fronts, providing a trusted platform for extracting and purifying bioactive ingredients, intermediates, and APIs (Active Pharmaceutical Ingredients).
Technical Specifications Supporting High-Volume Distillation
The AKR-1020 Rotary Evaporator is built to handle large-scale processes with an evaporation capacity of 20L, supported by a φ355mm/φ95 flange rotary flask. This capacity ensures that large batches of solvent-containing mixtures can be processed efficiently, reducing the time and energy requirements per cycle.
The collection flask offers 10L capacity with dual flange interfaces (φ280mm + φ60/φ50), accommodating substantial condensate volumes and facilitating rapid removal without interrupting ongoing distillation. The entire process is stabilized under a vacuum pressure of 0.095 Mpa, which significantly lowers boiling points and enhances solvent recovery speed.
The heating power of 5000W allows rapid thermal ramp-up across a wide temperature range from room temperature to 180°C, while ±1°C temperature accuracy ensures optimal safety and reproducibility for thermally sensitive pharmaceutical substances.
For additional technical insights and compatible lab equipment, Equilrxnlab’s full product catalog offers a curated selection tailored for pharmaceutical and chemical laboratories.
Efficient Condensation System for Large-Scale Operations
Efficient condensation is pivotal in rotary evaporation, especially at industrial volumes. The Large-Scale Rotary Evaporator for Pharmaceutical Applications integrates a high-performance condenser system with 0.94㎡ total surface area, composed of a main condenser (φ130×700mm) and auxiliary sections. This configuration accelerates vapor condensation and minimizes solvent loss, ensuring environmental safety and cost efficiency.
Its boiler flask—measuring φ450×260mm with an approximate capacity of 41L—supports continuous feed and recirculation systems, ideal for extended evaporation cycles common in pharmaceutical manufacturing workflows.
Operational Versatility with Adjustable Rotation and Lifting
Rotary evaporation depends on consistent mixing and solvent exposure. This model provides a rotational speed range of 0–120 rpm, allowing technicians to optimize flow dynamics based on solvent properties and viscosity. The integrated motor ensures stable torque output even at low speeds, supporting delicate separation procedures.
An important ergonomic feature is the 150mm lifting stroke for the heating bath, which simplifies flask replacement, cleaning, and temperature adjustments. This electric lifting system enhances lab safety and streamlines workflow, especially when handling high-temperature processes.
Detailed video demonstrations of the AKR-1020’s features and laboratory integration can be found on Equilrxnlab’s YouTube channel, supporting best practices for setup and usage.
Application Scenarios in Pharmaceutical Manufacturing
The Large-Scale Rotary Evaporator for Pharmaceutical Applications is specifically engineered for drug development, compound extraction, and purification processes. Typical applications include:
- Solvent recovery during crystallization of APIs
- Extraction of herbal and botanical compounds
- Concentration of intermediates before formulation
- Recrystallization and compound refinement
- Purification of fermentation products
These use cases benefit from the system’s scalability, accuracy, and chemical resistance, making it suitable for both R&D facilities and full-scale pharmaceutical production environments.
For process engineers and lab managers seeking to integrate this equipment into GMP protocols, Equilrxnlab offers technical support and system configuration assistance via their contact page.
Space Optimization and User-Focused Design
Despite its high-volume capacity, the Large-Scale Rotary Evaporator for Pharmaceutical Applications is designed with compactness and practicality in mind. Its well-integrated structure enables installation in modular clean rooms or pilot plants where space constraints must be balanced with performance requirements.
All operational components, including the control panel, vacuum interface, and lift mechanism, are positioned for intuitive use, reducing training overhead and operational error. Process images, field use examples, and industry feedback are regularly shared on Equilrxnlab’s Instagram and Facebook platforms.
The Large-Scale Rotary Evaporator for Pharmaceutical Applications offered by Equilrxnlab presents a high-performance, precision-controlled solution for labs requiring efficient solvent recovery, large-volume evaporation, and temperature-sensitive processing. Its robust configuration, from 20L flask capacity to ±1°C accuracy, supports modern pharmaceutical and chemical processing demands with industrial-grade reliability.
