30L Glass Reactor

What is it?

Glass Reactor (also known as Jacketed Glass Reactor) is an ultra-large capacity temperature-controlled stirred vessel specifically designed for production-scale validation, complete process scale-up, and early commercial manufacturing. It is widely used in chemical synthesis, pharmaceutical production, and fine chemical development. This 30L Glass Reactor adopts a high-borosilicate glass body with 30L material capacity and a 16L jacket structure, achieving efficient heating and cooling through external circulating medium. It supports precise temperature control, powerful stirring, and highly flexible configurations, making it suitable for complex industrial processes such as vacuum operations, reflux, continuous reactions, distillation, and crystallization.

Most suitable laboratories and project stages

• Pharmaceutical production-scale and commercial pilot labs
• Chemical process development and industrial scale-up centers
• Technology transfer and full production amplification laboratories
• Contract manufacturing organizations (CMO) and pilot-to-production facilities
• Application-oriented R&D labs with complete production goals
• Enterprise / research institute platforms focused on industrial-scale production validation

What scale-up pain points does it solve for you?

• Pilot-scale data fails to predict real commercial production behavior, leading to repeated failures and extremely high re-engineering costs
• Industrial-scale dominance of heat transfer, mass transfer, shear forces, dead zones, and local overheating effects
• Poor long-term stability, large batch-to-batch variation, and low reproducibility in continuous operations, impacting commercial reliability
• Complete loss of control over crystallization, precipitation, and crystal form at large scale, causing severe drops in purity/yield
• Exponentially increased safety risks with strong exothermic reactions, flammable solvents, or corrosive media
• Lack of reliable design basis for industrial reactors, resulting in large-scale late rework, delays, and high costs
• Difficulty in quickly preparing sufficient commercial-grade samples for trials, stability studies, or customer validation

Core technical features (why these parameters matter for scale-up)

• 30L material capacity + 16L jacket — Ultra-large heat exchange area for realistic industrial-grade thermal behavior simulation
• -120°C to +300°C ultra-wide temperature range — Supports extreme temperature difference validation at industrial scale with high precision control
• Fluorine-coated stainless steel stirring paddle — High corrosion resistance, suitable for industrial-scale aggressive media
• 0–450 rpm powerful adjustable stirring — High-torque output to simulate complete industrial stirring power and shear forces
• 6 customizable ports + 2L constant pressure funnel — Supports continuous feeding, multi-point monitoring, vacuum/reflux, and complex industrial processes
• Large 260mm coverage diameter — Significantly reduces dead zones and improves industrial mixing uniformity
• High-borosilicate double-walled structure — Transparent for real-time observation of industrial scale-up + effective insulation
• Optional explosion-proof motor/control box — Ensures safety for hazardous industrial-scale processes

Typical scale-up validation experiments

• Full process scale-up verification (Pilot → Production)
• Continuous / long-duration reaction stability testing (days to weeks)
• Industrial-scale crystallization, precipitation, and polymorph control
• Heat/mass transfer and stirring/shear industrial amplification studies
• Validation of thermally sensitive or highly exothermic/endothermic reactions
• Multi-batch reproducibility and process robustness testing
• Production-scale sample preparation for commercial trials, stability studies, and regulatory submission
• Generation of comprehensive design basis data for industrial reactors

Why choose 30L and above capacity?

• Extremely close to real production conditions — Heat transfer, mass transfer, and shear effects fully dominant
• Can validate all critical scale-up parameters — Temperature gradients, power consumption, local overheating, crystallization behavior
• Provides highly credible design basis for industrial reactors — Accurate parameters, material balance, and energy estimates
• Ideal for commercial demos & large-scale sample preparation — Quickly produces kilogram-to-ton-scale quantities for validation and approval
• Exceptional data reproducibility — Maximum batch-to-batch consistency, dramatically reduces production risks and costs

Recommended Compatible Equipment

• Low-Temperature Circulator — Provides stable low-temperature fluid for the jacket
• Heating Circulator — Supports precise high-temperature applications up to 300°C
• Vacuum Pump — Enables reduced-pressure reactions and solvent removal
• Glass Condenser — Efficient reflux, distillation, and solvent recovery
• Temperature Controller — High-accuracy PID regulation across the process

Demo Video & More Options

Want to see the full process of installation, temperature control, stirring, feeding, and cleaning? Watch product operation demo video

Need other capacities or special configurations? Browse the Glass Reactor Full Series, including 1L to 200L models.

Require custom port layout, stirring configuration, explosion-proof upgrades, or industrial scale-up consultation? Contact us for professional solutions and quotations.