1. What is it?

The double jacketed glass reactor — also known as double layer jacketed glass reactor — is a high-performance temperature-controlled stirred vessel designed for laboratory and pilot-scale chemical synthesis, pharmaceutical development, and fine chemical process research. This 5L model features a 5L material capacity inner vessel made of high-borosilicate glass, with a 3.1L mezzanine jacket for efficient heating and cooling circulation. It supports precise temperature regulation, variable-speed stirring, and flexible modular configurations, making it suitable for vacuum, reflux, multi-step reactions, and more.

2. What problems does it solve for you?

Temperature instability or large fluctuations during highly exothermic/endothermic reactions — the 3.1L jacket and PT100 probe enable fast, accurate, and uniform thermal exchange.
Uneven mixing, bottom sedimentation, local overheating, or incomplete reactions — especially noticeable at 5L scale — addressed by the high-torque, 0–1350 rpm adjustable stirring system and fluorine-coated paddle.
Leakage, contamination, or vacuum loss in longer runs or higher-volume operations — prevented by PTFE composite seals and precision-machined flanges.
Lab-scale data that is insufficiently representative for reliable pilot-scale transition — the 5L volume provides more meaningful, reproducible results that better bridge to larger scales.
Difficult post-reaction cleaning and persistent residues with increased material quantities — optional spray cleaning device simplifies maintenance and reduces downtime.
Safety risks when scaling up flammable, explosive, or corrosive reactions — optional explosion-proof motor and control box add essential protection.
Energy inefficiency, condensation buildup, and heat loss during extended experiments — optional insulated clothing minimizes these issues and improves overall thermal stability.

This 5L double jacketed glass reactor effectively bridges laboratory testing and preliminary pilot-scale work, delivering reliable, high-quality data while significantly reducing trial-and-error costs, risks, and development timelines.

3. What are the product features?

Balanced capacity & thermal efficiency — 5L material capacity + 3.1L mezzanine jacket for excellent heat transfer and uniform temperature distribution
Ultra-wide temperature range — -120°C to +300°C, ideal for cryogenic, high-temperature, and everything in between
Superior chemical resistance — Fluorine-coated stainless steel stirring paddle withstands strong acids, bases, halogens, and aggressive organic solvents
Powerful adjustable stirring — 0–1350 rpm stepless speed control with gimbal connection for smooth, stable, low-vibration operation
Highly flexible ports — 5 customizable ports supporting 500 ml constant pressure funnel, sensors, sampling, vacuum lines, condensers, and more
High-precision monitoring — PT100 sensor probe for real-time, accurate temperature feedback
Safety & upgrade options — Optional explosion-proof motor and control box for hazardous environments
Excellent visibility & stability — Transparent glass structure allows full real-time observation; compact yet robust design ensures mechanical stability
Easy maintenance features — Optional insulated clothing reduces heat loss and condensation; optional spray cleaning device enables quick rinsing

Recommended Compatible Equipment

- Low-Temperature Circulator — Maintains stable sub-zero jacket temperatures for cryogenic reactions
- Rotary Evaporator — Efficient post-reaction solvent removal and concentration
- Vacuum Pump — Enables distillation, filtration, and vacuum-assisted reactions

Refrigerated Chiller — Provides consistent jacket cooling and thermal regulation
Overhead Stirrer — Supports high-viscosity or challenging mixing needs

Demo Video & More Options See the full installation, temperature control, stirring, feeding, and cleaning process in action: Watch product operation demo video

Looking for other volumes or configurations? Browse the complete Double Jacketed Glass Reactor Series — including 1L, 2L, 3L, 10L, 20L and more.

Need custom port configuration, specialized stirring paddle, explosion-proof upgrades, or other modifications? Contact us for professional recommendations and quotations.

We provide worldwide shipping for all laboratory equipment. Every order is carefully packaged to ensure safe delivery. If the item is in stock, it will be shipped within 3–7 business days after payment confirmation. For out-of-stock items, we will inform you of the estimated shipping time based on the specific product.

Shipping Methods: DHL, FedEx, UPS, or sea freight (depending on order size and destination)
Estimated Delivery Time:

Asia: 5–10 business days
Europe & North America: 7–12 business days
South America & Africa: 10–15 business days
Sea freight: subject to actual transit time

Tracking: A tracking number will be provided via email once the shipment has been dispatched.
Customs & Duties: Buyers are responsible for any import taxes or customs duties required by their country or region.

For bulk orders, custom packaging, or special shipping arrangements, please contact our team for personalized assistance at lab@equilrxnlab.com.

Product specifications

High Pressure Reactor 5L Specifications

Parameter	AKF-5L
Material Capacity (L)	5L
Mezzanine Capacity (L)	3.1
Number of Ports	5 (Customizable)
Constant Pressure Funnel	500ML
Stirring Paddle	Stainless Steel Covered with Fluorine Material
Coverage Diameter (mm)	200
Inner Cylinder Diameter (mm)	170
Outer Cylinder Diameter (mm)	230
Vessel Height (mm)	430
Rotational Speed (rpm)	0–1350
Stirring Shaft Diameter (mm)	8
Stirring Connection	Gimbal Connection
Voltage Frequency	220V / 50Hz
Temperature Range	-120°C to +300°C
Temperature Probes	PT100 Sensor Probe
Explosion-proof Control Box	Optional
Insulated Clothing	Optional
Explosion-proof Motor	Optional

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Application Scenarios

Pharmaceutical Intermediate & API Synthesis (Early to Mid-Stage Development) Ideal for medium-scale synthesis of key drug intermediates and APIs during process development and optimization. The 5L capacity provides more representative data than smaller volumes, while the -120°C to +300°C range and precise PT100 control ensure high reproducibility and purity.
Low-Temperature Grignard, Organometallic & Cryogenic Reactions Perfect for reactions requiring sub-zero temperatures (down to -78°C or lower). The stable cryogenic performance, combined with the fluorine-coated paddle’s excellent chemical resistance, enables safe handling of highly reactive and corrosive reagents.
High-Temperature Organic Synthesis & Solvothermal Reactions Well-suited for polymerization, solvothermal synthesis, and other high-heat processes up to +300°C. The 3.1L mezzanine jacket and optional insulation deliver efficient, uniform heating with minimal energy loss during extended operations.
Distillation, Reflux, Solvent Recovery & Fractionation Easily configured with condensers, receivers, and vacuum systems for atmospheric or reduced-pressure distillation and efficient solvent recycling. The five customizable ports allow flexible setup of reflux, fractionation, and collection systems.
Crystallization & Polymorph Screening Critical for controlling crystal size, morphology, and polymorphism with high purity requirements. Precise temperature gradients and adjustable 0–1350 rpm stirring enable fine-tuned supersaturation and highly reproducible crystallization outcomes.
Multi-Step Reactions, Condition Screening & Route Optimization Supports sequential reagent addition, parameter exploration, and parallel testing of different conditions. The quick assembly, flexible port layout, and real-time visual monitoring make it ideal for rapid iteration and route comparison.
Lab-to-Pilot Scale Process Validation & Scale-Up Bridge Generates reliable, representative data at 5L scale that bridges early lab experiments to pilot/production. Helps significantly reduce scale-up risks, minimize costly re-optimization, and shorten overall development timelines.

These represent the most common applications of the 5L double jacketed glass reactor in pharmaceutical R&D, fine chemical development, and materials science. If your process involves unique requirements (e.g., high-viscosity systems, gas-liquid reactions, photocatalysis, or special handling), feel free to contact us for compatibility evaluation and customization options.

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Multiple stirring paddles available for your selection

According to the different properties and viscosities of materials, a variety of stirring paddles are available for your selection. The standard configuration includes ABCD types of stirring rods, with the A-type paddle recommended for the bottle neck, and custom-made EF and G types of stirring rods are available as well